Showing posts with label animal health. Show all posts
Showing posts with label animal health. Show all posts
Wednesday, August 8, 2012
Thursday, February 23, 2012
Thursday, July 28, 2011
Tuesday, January 18, 2011
Friday, October 8, 2010
Friday, September 17, 2010
Tuesday, August 17, 2010
PREVENTING MILKY EYES IN SENIOR DOGS
http://blogs.dogster.com/living-with-dogs/milk-thistle-and-senior-dogs/2010/08/
I'd be happy to hear comments on this...have you tried it?
I'd be happy to hear comments on this...have you tried it?
Monday, December 8, 2008
From Alternet: Red Wine and Marijuana can help prevent Alzheimer's
Attacking Alzheimer's with Red Wine and Marijuana
By Tom Jacobs, Miller-McCune.com. Posted December 8, 2008.
Two new studies point to a wonderful way to ward off Alzheimer's disease and other forms of age-related memory
This article first appeared on Miller-McCune.com.
Two new studies suggest that substances usually associated with dulling the mind -- marijuana and red wine -- may help ward off Alzheimer's disease and other forms of age-related memory loss. Their addition comes as another study dethrones folk remedy ginkgo biloba as proof against the disease.
At a November meeting of the Society of Neuroscience in Washington, D.C., researchers from Ohio State University reported that THC, the main psychoactive substance in the cannabis plant, may reduce inflammation in the brain and even stimulate the formation of new brain cells.
Meanwhile, in the Nov. 21 issue of the Journal of Biological Chemistry, neurologist David Teplow of the University of California, Los Angeles reported that polyphenols -- naturally occurring components of red wine -- block the formation of proteins that build the toxic plaques thought to destroy brain cells. In addition, these substances can reduce the toxicity of existing plaques, thus reducing cognitive deterioration.
Together, the studies suggest scientists are gaining a clearer understanding of the mechanics of memory deterioration and discovering some promising approaches to prevention.
Previous research has suggested that polyphenols -- which are found in high concentrations in tea, nuts and berries, as well as cabernets and merlots -- may inhibit or prevent the buildup of toxic fibers in the brain. These fibers, which are primarily composed of two specific proteins, form the plaques that have long been associated with Alzheimer's disease.
UCLA's Teplow and his colleagues monitored how these proteins folded up and stuck to each other to produce aggregates that killed nerve cells in mice. They then treated the proteins with a polyphenol compound extracted from grape seeds. They discovered the polyphenols blocked the formation of the toxic aggregates.
"What we found is pretty straightforward," Teplow declared. "If the amyloid beta proteins can't assemble, toxic aggregates can't form, and, thus, there is no toxicity." If this also proves true in human brains, it means administration of the compound to Alzheimer's patients could "prevent disease development and also ameliorate existing disease," he said. Human clinical trials are upcoming.
At Ohio State, researchers led by psychologist Gary Wenk are studying the protective effects of tetrahydrocannabinol, commonly known as THC. They found that administering a THC-like synthetic drug to older rats performed better at a memory test than a control group of non-medicated elderly rodents.
In some of the rats, the drug apparently lowered inflammation in the hippocampus -- the region of the brain responsible for short-term memory. It also seems to have stimulated the generation of new brain cells.
"When we're young, we reproduce neurons and our memory works fine," said co-author Yannick Marchalant, another Ohio State psychologist. "When we age, the process slows down, so we have a decrease in new cell formation in normal aging. You need those cells to come back and help form new memories, and we found that this THC-like agent can influence creation of those cells."
Wenk added two cautionary notes to his report. First, to be effective, any such treatment along these lines would have to take place before memory loss is obvious. Second, the researchers still have much work to do.
"We need to find exactly which receptors are most crucial" to the generation of new brain cells, he said. This discovery would "ideally lead to the development of drugs that specifically activate those receptors."
In the meantime, should aging baby boomers who are worried about old-age mental impairment light up a joint? Wenk was cautious in his answer, no doubt because marijuana is suspected to be harmful to health in other ways.
"Could people smoke marijuana to prevent Alzheimer's disease if the disease is in the family? We're not saying that, but it might actually work," he said. "What we are saying is it appears that a safe, legal substance the mimics those important properties of marijuana can work on receptors in the brain to prevent memory impairments in aging. So that's really hopeful."
Tom Jacobs is a veteran journalist with more than 20 years experience at daily newspapers. He has served as a staff writer for the Los Angeles Daily News and the Santa Barbara News-Press. His work has also appeared in the Los Angeles Times, Chicago Tribune and Ventura County Star.
By Tom Jacobs, Miller-McCune.com. Posted December 8, 2008.
Two new studies point to a wonderful way to ward off Alzheimer's disease and other forms of age-related memory
This article first appeared on Miller-McCune.com.
Two new studies suggest that substances usually associated with dulling the mind -- marijuana and red wine -- may help ward off Alzheimer's disease and other forms of age-related memory loss. Their addition comes as another study dethrones folk remedy ginkgo biloba as proof against the disease.
At a November meeting of the Society of Neuroscience in Washington, D.C., researchers from Ohio State University reported that THC, the main psychoactive substance in the cannabis plant, may reduce inflammation in the brain and even stimulate the formation of new brain cells.
Meanwhile, in the Nov. 21 issue of the Journal of Biological Chemistry, neurologist David Teplow of the University of California, Los Angeles reported that polyphenols -- naturally occurring components of red wine -- block the formation of proteins that build the toxic plaques thought to destroy brain cells. In addition, these substances can reduce the toxicity of existing plaques, thus reducing cognitive deterioration.
Together, the studies suggest scientists are gaining a clearer understanding of the mechanics of memory deterioration and discovering some promising approaches to prevention.
Previous research has suggested that polyphenols -- which are found in high concentrations in tea, nuts and berries, as well as cabernets and merlots -- may inhibit or prevent the buildup of toxic fibers in the brain. These fibers, which are primarily composed of two specific proteins, form the plaques that have long been associated with Alzheimer's disease.
UCLA's Teplow and his colleagues monitored how these proteins folded up and stuck to each other to produce aggregates that killed nerve cells in mice. They then treated the proteins with a polyphenol compound extracted from grape seeds. They discovered the polyphenols blocked the formation of the toxic aggregates.
"What we found is pretty straightforward," Teplow declared. "If the amyloid beta proteins can't assemble, toxic aggregates can't form, and, thus, there is no toxicity." If this also proves true in human brains, it means administration of the compound to Alzheimer's patients could "prevent disease development and also ameliorate existing disease," he said. Human clinical trials are upcoming.
At Ohio State, researchers led by psychologist Gary Wenk are studying the protective effects of tetrahydrocannabinol, commonly known as THC. They found that administering a THC-like synthetic drug to older rats performed better at a memory test than a control group of non-medicated elderly rodents.
In some of the rats, the drug apparently lowered inflammation in the hippocampus -- the region of the brain responsible for short-term memory. It also seems to have stimulated the generation of new brain cells.
"When we're young, we reproduce neurons and our memory works fine," said co-author Yannick Marchalant, another Ohio State psychologist. "When we age, the process slows down, so we have a decrease in new cell formation in normal aging. You need those cells to come back and help form new memories, and we found that this THC-like agent can influence creation of those cells."
Wenk added two cautionary notes to his report. First, to be effective, any such treatment along these lines would have to take place before memory loss is obvious. Second, the researchers still have much work to do.
"We need to find exactly which receptors are most crucial" to the generation of new brain cells, he said. This discovery would "ideally lead to the development of drugs that specifically activate those receptors."
In the meantime, should aging baby boomers who are worried about old-age mental impairment light up a joint? Wenk was cautious in his answer, no doubt because marijuana is suspected to be harmful to health in other ways.
"Could people smoke marijuana to prevent Alzheimer's disease if the disease is in the family? We're not saying that, but it might actually work," he said. "What we are saying is it appears that a safe, legal substance the mimics those important properties of marijuana can work on receptors in the brain to prevent memory impairments in aging. So that's really hopeful."
Tom Jacobs is a veteran journalist with more than 20 years experience at daily newspapers. He has served as a staff writer for the Los Angeles Daily News and the Santa Barbara News-Press. His work has also appeared in the Los Angeles Times, Chicago Tribune and Ventura County Star.
Sunday, October 19, 2008
10 Human medications harmful to your dog
Top 10 Human Medications That Poison Our Pets
Although pet parents are well aware of poisons lurking around their home, many don’t realize that some of the biggest culprits are sitting right on their own nightstands. In 2007, the ASPCA Animal Poison Control Center received 89,000 calls related to pets ingesting over-the-counter and prescription medications. To help you prevent an accident from happening, our experts have created a list of the top 10 human medications that most often poison our furry friends.
If you suspect your pet has ingested any of the following items, please call your veterinarian or the ASPCA Animal Poison Control Center’s 24-hour hotline at (888) 426-4435. And remember to keep all medications tucked away in bathroom cabinets—and far from curious cats and dogs.
NSAIDs
NSAIDs (non-steroidal anti-inflammatory drugs) like ibuprofen or naproxen are the most common cause of pet poisoning in small animals, and can cause serious problems even in minimal doses. Pets are extremely sensitive to their effects, and may experience stomach and intestinal ulcers and—in the case of cats—kidney damage.
Antidepressants
Antidepressants can cause vomiting and lethargy and certain types can lead to serotonin syndrome—a condition marked by agitation, elevated body temperature, heart rate and blood pressure, disorientation, vocalization, tremors and seizures.
Acetaminophen
Cats are especially sensitive to acetaminophen, which can damage red blood cells and interfere with their ability to transport oxygen. In dogs, it can cause liver damage and, at higher doses, red blood cell damage.
Methylphenidate (for ADHD)
Medications used to treat ADHD (Attention Deficit Hyperactivity Disorder) in people act as stimulants in pets and can dangerously elevate heart rates, blood pressure and body temperature, as well as cause seizures.
Fluorouracil
Fluorouracil—an anti-cancer drug—is used topically to treat minor skin cancers and solar keratitis in humans. It has proven to be rapidly fatal to dogs, causing severe vomiting, seizures and cardiac arrest even in those who’ve chewed on discarded cotton swabs used to apply the medication.
Isoniazid
Often the first line of defense against tuberculosis, isoniazid is particularly toxic for dogs because they don’t metabolize it as well as other species. It can cause a rapid onset of severe seizures that may ultimately result in death.
Pseudoephedrine
Pseudoephedrine is a popular decongestant in many cold and sinus products, and acts like a stimulant if accidentally ingested by pets. In cats and dogs, it causes elevated heart rates, blood pressure and body temperature as well as seizures.
Anti-diabetics
Many oral diabetes treatments—including glipizide and glyburide—can cause a major drop in blood sugar levels of affected pets. Clinical signs of ingestion include disorientation, lack of coordination and seizures.
Vitamin D derivatives
Even small exposures to Vitamin D analogues like calcipotriene and calcitriol can cause life-threatening spikes in blood calcium levels in pets. Clinical signs of exposure—including vomiting, loss of appetite, increased urination and thirst due to kidney failure—often don't occur for more than 24 hours after ingestion.
Baclofen
Baclofen is a muscle relaxant that can impair the central nervous systems of cats and dogs. Some symptoms of ingestion include significant depression, disorientation, vocalization, seizures and coma, which can lead to death.
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